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Achieving and maintaining a healthy weight can often feel like an uphill battle, but personalized, medically supervised weight loss programs offer an effective and supportive solution. These programs are tailored specifically to each individual's unique health needs and weight loss goals, ensuring a safe and sustainable approach to shedding pounds.
By working closely with MacroFusion, participants benefit from a comprehensive evaluation that includes medical history, current health status, lifestyle habits, and any underlying conditions that may affect weight loss. This thorough assessment allows for the creation of a customized plan that addresses not just diet and exercise, but also behavioral and psychological factors.
With the support and expertise of our dedicated healthcare team, individuals are empowered to achieve their weight loss goals and maintain a healthier lifestyle for years to come.
Semaglutide & Tirzepatide Dosing/Protocol
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SEMAGLUTIDE
What is Semaglutide?
Semaglutide is a medication primarily known for its effectiveness in treating type 2 diabetes. However, its impressive ability to aid in weight loss that has garnered widespread attention.
Compounding pharmacies provide a generic version of Semaglutide oftentimes in combination with Vitamin B-12. It is most commonly given as a subcutaneous injection in the lower belly once weekly.
Its versatility and effectiveness make Semaglutide a top choice for healthcare professionals and patients alike in the quest for weight loss and better health.
How does it work in the body?
The secret to Semaglutide’s success lies in its clever mimicry of the hormone glucagon-like peptide-1 (GLP-1), which plays a pivotal role in appetite regulation.
By emulating the hormone incretin, Semaglutide tricks the body into feeling fuller for longer periods, thus reducing the urge to eat. This process is facilitated by slowing down gastric emptying, meaning food stays in your stomach for a longer duration.
This ingenious mechanism not only helps in controlling calorie intake but also assists in making healthier food choices, as you’re less likely to reach for quick, high-calorie snacks when you feel satiated.
Positive effects of Semaglutide
The benefits of Semaglutide extend far beyond just appetite suppression. Clinical studies have shown that individuals using Semaglutide experience significant and sustained weight loss, making it a powerful tool in the battle against obesity.
Moreover, for those with type 2 diabetes, it offers the added advantage of improving blood sugar control, thereby tackling two major health issues simultaneously.
Users of Semaglutide have reported feeling more in control of their eating habits and a lowered weight set point, leading to a more positive relationship with food and overall well-being.
What does this mean?
Semaglutide stands out as a beacon of hope for many striving to achieve their weight loss goals. It’s not just about shedding pounds; it’s about embracing a healthier, more balanced lifestyle.
As with any medication, it’s crucial to consult with healthcare professionals to determine if Semaglutide is the right fit for you.
TIRZEPATIDE
What is Tirzepatide?
Tirzepatide is an experimental drug that was Food and Drug Administration (FDA)-approved in 2020 to treat Type 2 diabetes (Mounjaro), and approved in 2023 to weight-loss (Zepbound).
Tirzepatide belongs to a new class of drugs.
It mimics the effects of a hormone molecule called GLP-1 (glucagon-like peptide-1) receptor agonists, such as semaglutide. Now, add the action of GIP (glucose-dependent insulinotropic polypeptide) receptor agonism to the mix. You are getting more bang for your buck with this medication.
Tirzepatide is the forerunner of a new approach to both controlling diabetes and losing weight.
How It Works:
Tirzepatide blocks both GLP-1 and GIP receptors, thus acting like two drugs by way of one molecule.
It not only reduces appetite and prompts the pancreas to pump out more insulin when blood sugars are elevated – just like the GLP-1 drugs – but it also stimulates the pancreas to produce additional insulin and break down stored fat.
Together, these actions cause even bigger weight loss and better control of blood sugars than medications acting only on GLP-1.
Tirzepatide acts on two fronts to lower appetite, cut calorie intake and burn fat into a leaner body mass.
Positive Effects of Tirzepatide:
Clinical trials have shown Tirzepatide to be highly effective in reducing body weight and improving glycemic control in individuals with type 2 diabetes.
The percentage of weight loss with tirzepatide substantially exceeded that achieved with other diabetes medicines, and this could be a real game-changer for people suffering from obesity and associated conditions.
Tirzepatide also improved other hallmarks and risk factors for cardiovascular disease, such as arterial blood pressure and lipid levels.
If clinical trials hold true in the real world, this could be a major advance in metabolic health.
What Does this Mean?
While both Tirzepatide and Semaglutide are GLP-1 receptor agonists used in the treatment of type 2 diabetes and weight management, There are important differences between the two drugs.
Tirzepatide is not only a GLP-1 receptor agonist, (like semaglutide), but also a gastrointestinal hormone-incretin that acts on GIP receptors. This dual-action of Tirzepatide versus the single-action of Semaglutide could be hypothesised to explain Tirzepatide’s modest superiority in mediating weight loss and glycaemic control, as has become evident in direct comparative studies.
On the whole, Tirzepatide has emerged as a potent therapeutic for patients whose treatment goals have not been met using currently available drugs.
